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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Glycine, the smallest amino acid, confers neuroprotection against d-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain

Fig. 1

Experimental design, cytoprotective and antioxidant effects of glycine in d-galactose-treated in HT22 cells. a Experimental design of experimental work for the drug treatment in C57BL/6 mice and behavioral analysis. bd Results of MTT (cell viability) assay and their relative histogram in neuronal HT22 cells. Number of experiment (N = 3). e, f Representative histograms of reactive oxygen species (ROS measured as DCF level) and lipid peroxidation (LPO measured MDA level) assays of Gly against D-gal in HT22 cells. The data are shown as the mean ± SEM of triplicate wells for in vitro experiments are representative of three independent experiments. Significance: Asterisk (*) sign indicated significant difference from the normal saline-treated control group; hash (#) sign indicated significant difference from d-gal-treated group. Significance: *P ≤ 0.05, **P ≤ 0.01; ***P ≤ 0.001; #P ≤ 0.05, ##P ≤ 0.01. n.s no significance

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