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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: NFATc2-dependent epigenetic upregulation of CXCL14 is involved in the development of neuropathic pain induced by paclitaxel

Fig. 3

The screening for targeted gene of NAFTc2 binding following paclitaxel treatment. a Following the microarray experiment, heat map of 419 genes which increased by 2.5 folds in paclitaxel treatment rats. b The intersection of NFATc2 ChIP sequence data with gene expression profile data showed that CXCL14 and Tnbs4 may be regulated by NFATc2 in dorsal horn. c, d RT-PCR showed CXCL14 but not Thbs4 was significantly increased on day 21 following overexpression of NFATc2 in interspinal AAV-hSyn-NFATc2-EGFP-injected rats (**P < 0.01 vs the AAV-hSyn-EGFP-injected rats, n = 5 per group)

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Journal of Neuroinflammation

ISSN: 1742-2094