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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Corticosteroid receptor rebalancing alleviates critical illness-related corticosteroid insufficiency after traumatic brain injury by promoting paraventricular nuclear cell survival via Akt/CREB/BDNF signaling

Fig. 3

MP and CORT differentially affected neuronal survival in the PVN by regulating the expression and activation of MR and GR after TBI. a Representative western blot images showing total/nuclear MR and GR expression. b Quantification of total/nuclear MR and GR expression. The relative band density was measured with ImageJ (1.49 V) and normalized to that of β-actin/histone H3, and the percent expression compared to that of sham controls was calculated for each sample. c Representative images of GR (red, white arrow) and MR (green, yellow arrow) immunofluorescence in the PVN. *P < 0.05 versus the sham control group; #P < 0.05 versus the TBI control group. The data are presented as the means ± SD of 6 animals per group

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