Fig. 7

Myeloid TonEBP is required for blocking LPS-induced loss of short-term memory. a LPS (3 μg per animal) or vehicle (CTL:1x PBS) was injected into the left ventricle of male TonEBPfl/fl,LysM-cre mice (KO in b) and their TonEBPfl/fl littermates (WT in b). Two weeks later, passive avoidance test was performed followed by perfusion fixation of the brains. Latency in seconds in passive avoidance test. Mean + SE, n = 3–6. *P < 0.05 B NeuN immunostaining in CA3 region of hippocampus. Florescence intensity of the immunostaining was shown on the right. Bar = 50 μm. Mean + SE, n = 3. #P < 0.05, compared to CTL. *P < 0.05 compared to TonEBP fl/fl