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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Ocular macrophage origin and heterogeneity during steady state and experimental choroidal neovascularization

Fig. 4

Fate mapping of macrophages subsets after laser injury. a Breeding strategy for generation of MacGFP mice. b Experimental design for fate mapping of tissue resident macrophages. c Representative contour plots of GFP+ vs. GFP macrophage subsets. dk Quantitative analysis of GFP+ and GFP macrophage numbers for each subset in female (dg) and male (hk) mice. Oil = corn oil vehicle control, Tam = Tamoxifen. *p < 0.05; **p < 0.01; ***p < 0.001. Color = GFP− (black) or GFP+ (green) cells. N = 3–9 in male mice and N = 4–9 in female mice per group. Macrophage numbers were compared using the Brown-Forsythe and Welch ANOVA followed by Dunnett’s T3 multiple comparison

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