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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Ocular macrophage origin and heterogeneity during steady state and experimental choroidal neovascularization

Fig. 6

Single-cell RNA-seq analysis from human RPE-choroid samples. a UMAP dimension plot of 11 leukocyte clusters. b Dot plot of canonical macrophage, T cell, NK cell, B cell, and mast cell markers. c, d Violin plots of HLA.DMA (MHCII) and ITGAX (CD11C) gene expression in macrophage clusters. e, f Feature plots of HLA.DMA (MHCII) and ITGAX (CD11C) gene expression. g UMAP dimension plot grouped by donor (patients with nAMD are highlighted in blue [not EC enriched] and red [EC enriched])

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