Fig. 8
From: Minocycline reduces inflammatory response and cell death in a S100B retina degeneration model
Top diseases and biological function analysis of the differentially abundant proteins. a The significantly affected disease and biological functions in the retinal samples associated with the different treatment paradigms. Z-scores are represented by the colour orange, which indicates activation, and blue, which indicates inhibition of the associated functions. b Network of proteins associated with apoptosis in the comparison analysis between S100B and PBS. Colours red and green represent increment and decrement of protein abundance, respectively, with different colour intensities that correspond to the degree of differential expression. Proteins are depicted as different shapes, which represent the functional classes of the proteins (e.g., enzyme, transporter, ion channel)