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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Diesel exhaust impairs TREM2 to dysregulate neuroinflammation

Fig. 2

Diesel exhaust dysregulates markers of disease-associated microglia. WKY rats were exposed to diesel exhaust (0, 50, 150, or 500 μg/m3) by inhalation for 4 weeks. Changes in gene expression of the disease-associated microglia markers were analyzed by qRT-PCR. Stage 1 DAM markers Cx3cr1 and Lyz2 were analyzed in the frontal cortex (a, b) and the hippocampus (d, e). The stage 2 DAM marker Lpl was analyzed in the frontal cortex (c) and hippocampus (f). Data are reported as the mean ± SEM. *p < 0.05 when compared to control. #p < 0.05 compared between exposure groups (n = 7)

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