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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model

Fig. 3

Hv1 deletion reduced ROS production in the corpus callosum after LPC injection. a Representative images of 8-OHG and Iba-1 immunostaining in the CC of WT and Hv1−/− mice (scale bar, 50 μm; magnified images, 20 μm). b Quantification of the immunoreactivity of 8-OHG. Each point of WT mice, N = 6-8 mice; Hv1−/− mice, N = 6-8 mice. Data are shown as mean ± SD, *P < 0.05, **P < 0.01, two-way ANOVA with Dunnett’s post hoc test

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