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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model

Fig. 5

Hv1 deficiency rescued the spatial memory impairment induced by LPC treatment. (a and c) Representative motion trail of memory phase of WT and Hv1−/− mice at 10 dpi and 28 dpi. (b and d) Quantification of the Morris water maze test at 10 dpi and 28 dpi of WT and Hv1−/− mice, compared with the sham group. Each point of WT mice, N = 10-11 mice; Hv1−/− mice, N = 8-12 mice. Data are shown as mean ± SD, **P < 0.01, two-way ANOVA with Dunnett’s post hoc test

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