Fig. 2
NF-KB inhibition in microglia leads to white matter volume preservation. MRI volumetric analysis at postnatal day 15 comparing sham RA, HI IKKβflox/wt CSF-1R Cre− (HI Cre−), and HI IKKβflox/wt CSF-1R Cre+ (HI Cre+), using the BioSpec 94/30 imaging system is a 9.4 T horizontal bore magnet operates at 400 MHz and runs ParaVision™4.0 software. a Coronal (top) and axial (bottom) brain slices. b The two lateral ventricle volumes measured by paravision software. c Total brain volume includes brain volume + lateral ventricle volume measured by paravision software. d The ratio of both lateral ventricle volumes to total brain volume measured by paravision software. N = 10 animals/group. Scatter dot plot showing mean ± SE. indicates*P < 0.05. **P ≤ 0.01