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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Prophylactic inhibition of NF-κB expression in microglia leads to attenuation of hypoxic ischemic injury of the immature brain

Fig. 5

NF-κB modulates microglial activation to an inflammatory, neurotoxic phenotype. a Immunostaining for all microglia (Iba1) in green (top) and CD 68 (marker of activated microglia M1 only) in red (middle). Co-localization in yellow indicating amount of activated microglia at postnatal day 15. * indicates lateral ventricle. Quantification of CD68/Iba1 per section. Scale bar = 100 μm N = 5 animals/group and 4 sections/animal. Scatter dot plot showing mean ± SE. ***P ≤ 0.001, ****P ≤ 0.0001

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