Fig. 6

Absence of CCL3 reduces axonal damage and number of macrophages/microglia after SCI. a Representative images of SMI-32 (green) and DAPI (blue) in wild-type and CCL3^–/– mice at day 5 after injury adjacent to the lesion epicenter. Arrows indicate SMI-32+ profiles. b Quantitative analysis revealing a reduced number of SMI-32+ cells in CCL3^–/– compared to wild-type mice. c Representative images of CD11b (red) and DAPI (blue) in wild-type and CCL3^–/– mice at day 5 after injury adjacent to the lesion epicenter. Arrows indicate CD11b+ staining in relation to a DAPI+ nucleus. d Quantitative analysis revealing a reduced number of CD11b+ cells in CCL3^–/– compared to wild-type mice. Scale bar = 80 μm. n = 5/group. * = p value < 0.05. Data points represent mean ± SEM