Fig. 1
From: Insulin inhibits inflammation-induced cone death in retinal detachment
RD causes a marked inflammatory response with increased cytokine and chemokine expression in both human and experimental models. Vitreous concentrations of a cytokines, b chemokines, and c growth factors from MH and RD groups of patients (34 MH and 41 RD samples; a t test or Mann-Whitney U test, *p < 0.0001 and $p = 0.009 versus control; b t test or Mann-Whitney U test, *p < 0.0001 and $p = 0.002 versus control; c t test *p = 0.002 versus control). Relative expression of d cytokine, e chemokine, and f growth factor mRNAs normalized with S26 expression quantified by RT-qPCR in mouse retina without RD and 4 days after RD (n = 6–8/group; Mann-Whitney U test *p < 0.01 and $p = 0.03 versus control). RD, retinal detachment; MH, macular hole. All values are reported as mean ± SEM