Fig. 16

Effect of miRNA-27a mimics and isoliquiritin in LPS+ATP-treated primary microglia cells. a mRNA expression of miRNA-27a. b Representative Western blots. c–h Protein levels of SYK, p-NF-κB, NLRP3, cleaved Caspase-1, IL-1β, and GSDMD-N. Data are presented as mean ± SEM (n = 3 per group). ##p < 0.01, compared to blank group; *p < 0.05, **p < 0.01, compared to LPS+ATP group