Fig. 4

Effects of isoliquiritin on miRNA-27a mRNA expression and protein levels of NLRP3 cascade in the hippocampus of LPS mice. a mRNA expression level of miRNA-27a. b Representative Western blots. c–h Protein levels of SYK, p-NF-κB, NLRP3, cleaved Caspase-1, IL-1β, and GSDMD-N. Data are presented as mean ± SEM (n = 3–4 per group). ^##p < 0.01, compared to control group; *p < 0.05, **p < 0.01, compared to LPS group