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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Oleanolic acid ameliorates intestinal alterations associated with EAE

Fig. 7

OA treatment modulated intestinal barrier function in differentiated Caco-2:HT29-MTX-E12 co-cultures subjected to an inflammatory stimulus. Differentiated Caco-2:HT29-MTX-E12 co-cultures at 75:25 proportions were stimulated with apical 100 ng/ml of TNFα (a, b) or basolateral 100 ng/ml of TNFα (c, d) for 24 h. a, d TEER values normalized to the untreated control; b, d FITC-dextran (FD-40) transport. The assays were performed in triplicates, n = 3. Results were expressed as the mean ± SEM. *p < 0.001 and **p < 0.01 vs control; and p < 0.001, ‡‡p < 0.01, and ‡‡‡p < 0.05 vs stimuli without OA

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