Skip to main content
Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model

Fig. 4

Effects of chronic noise exposure on the status of oxidative stress in the intestine. a–e Antioxidant capacities in cecal contents (n = 5–6). f–k mRNA expression levels of key enzymes in GSH/GST pathways and NOX2/4 in colon tissue (n = 6). l Enzyme-linked immunosorbent assay analysis of Nrf2 content in colon tissue (n = 5–6). Data are presented as the mean ± standard deviation. *P < 0.05, **P < 0.01 vs. WT CON group; #P < 0.05, ##P < 0.01 vs. APP/PS1 CON group. §, exposure effect, P < 0.05; ¶, genotype effect, P < 0.05; ǂ, interaction effect, P < 0.05. CON, control groups; NOISE, noise-exposed groups; WT, wild-type mice; APP/PS1, APP/PS1 transgenic mice

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094