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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model

Fig. 7

Circulatory abnormalities in neurotransmitters and inflammatory mediators following noise exposure. a–f Enzyme-linked immunosorbent assay analysis of the concentrations of neurotransmitters (5-HT and GABA) and inflammatory mediators (D-LAC, endotoxin, IL-6, and TNF) in each group (n = 5–7). Data are presented as the mean ± standard deviation. *P < 0.05, **P < 0.01 vs. WT CON group; #P < 0.05, ##P < 0.01 vs. APP/PS1 CON group. §, exposure effect, P < 0.05; ¶, genotype effect, P < 0.05; ǂ, interaction effect, P < 0.05. CON, control groups; NOISE, noise-exposed groups; WT, wild-type mice; APP/PS1, APP/PS1 transgenic mice

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Journal of Neuroinflammation

ISSN: 1742-2094