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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Comparisons of neuroinflammation, microglial activation, and degeneration of the locus coeruleus-norepinephrine system in APP/PS1 and aging mice

Fig. 3

Microglia accumulating around Aβ42+ plaques in the brain and spinal cord. a Iba-1 and Aβ42 co-staining in PFC, ACC, DG, CA3, and lumbar spinal cord from 12-month-old APP/PS1 mice showed that a large number of microglia activated and accumulated around the Aβ42+ plaques in the brain and in the grey matter of the spinal cord. b, c Iba-1 and Aβ42 colocalized areas (yellow color in a) in PFC were selected and quantified with Image J

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Journal of Neuroinflammation

ISSN: 1742-2094