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Table 1 Patient characteristics

From: Clinical evaluation of neuroinflammation in child-onset focal epilepsy: a translocator protein PET study

Patient Age,
years
Sex weight (kg) Age of onset (y) Epilepsy diagnosis (localization) AEDs Seizure frequency Seizure Types Etiology
1 17 M 53.6 6 FE (L-F) LTG, VPA, and ZNS Yearly Versive seizure
2 10 M 35.5 5 FE (R-O) CLB, VPA, SLM, and PER Daily CPS, SPS Ulegyria
3 22 M 68.3 19 FE (R-T) LEV Monthly CPS Tumor (low grade glioma)
4 6 M 34.9 4 FE (R-F) Monthly Versive seizure Autoimmune encephalitis
5 14 F 53.7 9 FE (R-T) LEV and CBZ Daily CPS Hippocampal sclerosis
6 4 M 15.1 0.5 WS VPA, ZNS, ESM, and LTG Daily Tonic seizure, epileptic spasms TSC
7 3 F 18.8 0.3 WS VGB, VPA, LEV, and GBP Daily Tonic seizure, epileptic spasms TSC
8 3 M 14.7 0.6 FE (L-F) PB and LTG Daily hypermotor seizure TSC2 mutation
9 13 F 29.0 0.2 FE (R-F) LTG, VPA, AZA, LCM Weekly sGTC 1p36 deletion
10 9 M 24.7 5 WS VPA and LTG Daily Tonic seizure, epileptic spasms TSC
11 11 M 38.1 6 FE (L-O) CBZ, PB, and PER Daily/weekly Visual SPS/sGTC Cerebral infarction
12 16 F 47.5 3 FE (R-F) LEV, LTG, CLB, and PER Monthly SPS Cavernous hemangioma
13 25 M 48.0 0.5 FE (R-F) TPM, CLB, LEV, and PER Yearly sGTC Sturge-Weber syndrome
14 8 M 23.0 4 FE (L-F) ZNS and CBZ Daily Automatism
15 5 M 18.6 3 FE (L-T) PB and CZP Daily Epileptic spasms, CPS Herpes encephalitis
16 11 M 35.9 7 FE (LR-F) LTG and CBZ Weekly Versive seizure
17 16 F 43.9 4 FE (R-F) VPA Daily Hypermotor seizure TSC
18 11 M 33.7 1.6 FE (R-F) CBZ and VPA Versive seizure TSC
19 10 M 58.5 5 LK CZP, ESM, LCM, DZP, and VPA Yearly CPS
20 7 F 20.1 1.5 FE (LR-F) VPA, PHT, and ZNS Daily Hypermotor seizure
21 22 F 42.0 2.3 FE (R-F) PHT, VPA, LTG, and PER Monthly SPS TSC
22 13 M 29.1 3.4 FE (L-P) LTG, ZNS, and VPA Daily Hypermotor, tonic FCD
23 19 M 61.5 13 FE (L-T) CBZ and PER Yearly Visual aura~sGTC
24 11 M 45.6 1.3 FE (L-F) LEV, SLM, and NZP Weekly brief tonic (CPS)
25 6 F 19.6 2.4 FE (R-F) VPA and PER subclinical seizure only TSC
26 1 F 8.6 0.8 WS VGB Daily epileptic spasms HME+FCD
27 13 F 53.8 5.4 FE (L-F) TPM, LEV, PER, and LTG Weekly SPS
  1. AEDs antiepileptic drugs, F Female, M male, FE focal epilepsies, L- left, R- right, F frontal, T temporal, O occipital, P parietal, WS West syndrome, LK Landau-Kleffner syndrome, LTG lamotrigine, VPA valproic acid, ZNS zonisamide, CLB clobazam, SLM sultiam, PER perampanel, LEV levetiracetam, CBZ carbamazepine, ESM ethosuximide, VGB vigabatrin, GBP gabapentin, PB phenobarbital, AZA acetazolamide, LCM lacosamide, TPM topiramate, DZP diazepam, PHT phenytoin, CPS complex partial seizures, SPS simple partial seizures, sGTC secondarily generalized tonic–clonic convulsion, TSC tuberous sclerosis complex, FCD focal cortical dysplasias, HME hemimegalencephaly