Table 1 Patient characteristics
Patient | Age, years | Sex | weight (kg) | Age of onset (y) | Epilepsy diagnosis (localization) | AEDs | Seizure frequency | Seizure Types | Etiology |
|---|---|---|---|---|---|---|---|---|---|
1 | 17 | M | 53.6 | 6 | FE (L-F) | LTG, VPA, and ZNS | Yearly | Versive seizure | – |
2 | 10 | M | 35.5 | 5 | FE (R-O) | CLB, VPA, SLM, and PER | Daily | CPS, SPS | Ulegyria |
3 | 22 | M | 68.3 | 19 | FE (R-T) | LEV | Monthly | CPS | Tumor (low grade glioma) |
4 | 6 | M | 34.9 | 4 | FE (R-F) | – | Monthly | Versive seizure | Autoimmune encephalitis |
5 | 14 | F | 53.7 | 9 | FE (R-T) | LEV and CBZ | Daily | CPS | Hippocampal sclerosis |
6 | 4 | M | 15.1 | 0.5 | WS | VPA, ZNS, ESM, and LTG | Daily | Tonic seizure, epileptic spasms | TSC |
7 | 3 | F | 18.8 | 0.3 | WS | VGB, VPA, LEV, and GBP | Daily | Tonic seizure, epileptic spasms | TSC |
8 | 3 | M | 14.7 | 0.6 | FE (L-F) | PB and LTG | Daily | hypermotor seizure | TSC2 mutation |
9 | 13 | F | 29.0 | 0.2 | FE (R-F) | LTG, VPA, AZA, LCM | Weekly | sGTC | 1p36 deletion |
10 | 9 | M | 24.7 | 5 | WS | VPA and LTG | Daily | Tonic seizure, epileptic spasms | TSC |
11 | 11 | M | 38.1 | 6 | FE (L-O) | CBZ, PB, and PER | Daily/weekly | Visual SPS/sGTC | Cerebral infarction |
12 | 16 | F | 47.5 | 3 | FE (R-F) | LEV, LTG, CLB, and PER | Monthly | SPS | Cavernous hemangioma |
13 | 25 | M | 48.0 | 0.5 | FE (R-F) | TPM, CLB, LEV, and PER | Yearly | sGTC | Sturge-Weber syndrome |
14 | 8 | M | 23.0 | 4 | FE (L-F) | ZNS and CBZ | Daily | Automatism | – |
15 | 5 | M | 18.6 | 3 | FE (L-T) | PB and CZP | Daily | Epileptic spasms, CPS | Herpes encephalitis |
16 | 11 | M | 35.9 | 7 | FE (LR-F) | LTG and CBZ | Weekly | Versive seizure | – |
17 | 16 | F | 43.9 | 4 | FE (R-F) | VPA | Daily | Hypermotor seizure | TSC |
18 | 11 | M | 33.7 | 1.6 | FE (R-F) | CBZ and VPA | – | Versive seizure | TSC |
19 | 10 | M | 58.5 | 5 | LK | CZP, ESM, LCM, DZP, and VPA | Yearly | CPS | – |
20 | 7 | F | 20.1 | 1.5 | FE (LR-F) | VPA, PHT, and ZNS | Daily | Hypermotor seizure | – |
21 | 22 | F | 42.0 | 2.3 | FE (R-F) | PHT, VPA, LTG, and PER | Monthly | SPS | TSC |
22 | 13 | M | 29.1 | 3.4 | FE (L-P) | LTG, ZNS, and VPA | Daily | Hypermotor, tonic | FCD |
23 | 19 | M | 61.5 | 13 | FE (L-T) | CBZ and PER | Yearly | Visual aura~sGTC | – |
24 | 11 | M | 45.6 | 1.3 | FE (L-F) | LEV, SLM, and NZP | Weekly | brief tonic (CPS) | – |
25 | 6 | F | 19.6 | 2.4 | FE (R-F) | VPA and PER | – | subclinical seizure only | TSC |
26 | 1 | F | 8.6 | 0.8 | WS | VGB | Daily | epileptic spasms | HME+FCD |
27 | 13 | F | 53.8 | 5.4 | FE (L-F) | TPM, LEV, PER, and LTG | Weekly | SPS | – |