|
Stubbe et al. [7]
|
30 min MCAO
|
CD4+ T cells and Tregs elevating in the peri-infarct and infarct area with MHCII+ DCs and MHCII+ macrophages after ischemic stroke
|
More CD4+ and Tregs elevating in the ischemic hemisphere consistent with increasing MHCII+ microglia, DCs and macrophages in the injured brain after ischemic stroke
|
2013
|
|
Vindegaard et al. [89]
|
pMCAO
|
Only a few CD3+ T cells infiltrating into the brain, predominantly located to the meningeal areas or in close proximity to a vessel, in the vicinity of the infarct with a few macrophage/microglia infiltrating the infarct area
|
A high number of macrophage/microglia infiltrating the infarct area and increasing T cell numbers within the infarct core and the corpus callosum
|
2017
|
|
Xie et al. [90]
|
90 min MCAO
|
Activated/memory phenotype of T cells (either CD4+ or CD8+) infiltrating the ischemic hemisphere
|
Greater proportion of activated/memory T cells than the acute phase with CD25, a T cell activation antigen, increasing in both brain-invading CD4+ and CD4− T cells
|
2018
|
