Stubbe et al. [7]
|
30 min MCAO
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CD4+ T cells and Tregs elevating in the peri-infarct and infarct area with MHCII+ DCs and MHCII+ macrophages after ischemic stroke
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More CD4+ and Tregs elevating in the ischemic hemisphere consistent with increasing MHCII+ microglia, DCs and macrophages in the injured brain after ischemic stroke
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2013
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Vindegaard et al. [89]
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pMCAO
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Only a few CD3+ T cells infiltrating into the brain, predominantly located to the meningeal areas or in close proximity to a vessel, in the vicinity of the infarct with a few macrophage/microglia infiltrating the infarct area
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A high number of macrophage/microglia infiltrating the infarct area and increasing T cell numbers within the infarct core and the corpus callosum
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2017
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Xie et al. [90]
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90 min MCAO
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Activated/memory phenotype of T cells (either CD4+ or CD8+) infiltrating the ischemic hemisphere
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Greater proportion of activated/memory T cells than the acute phase with CD25, a T cell activation antigen, increasing in both brain-invading CD4+ and CD4− T cells
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2018
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