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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Differential neurovirulence of Usutu virus lineages in mice and neuronal cells

Fig. 7

EU2 USUV strain is more virulent and persistent longer in different brain cells. Murine neuronal (a), human pericyte (b), and human endothelial (c) cells cultures were infected with USUV at a MOI of 0.1. Bright light images of CT- and USUV-infected neuron at 4 dpi (a) and endothelial cells at 6 dpi (c) show atypical CPE in EU2 condition while infection induces no CPE in pericytes at 4 dpi (b). Viral quantification for each cell type is expressed in TCID50/mL. Results are expressed as mean ± SEM of 3 independent experiments. *p < 0.05, **p < 0.01, and ***p < 0.001

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