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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson’s disease

Fig. 4

Behavioral motor disturbances were observed in the DSS and LPS + paraquat-treated animals. As shown in panel a, all DSS-treated mice exhibited reduced time spent on rotarod, relative to all other animals. Panel b illustrates that the DSS treatment initially (prior to LPS and paraquat) reduced home-cage locomotor activity. Thereafter, panel c illustrates that by the time of sacrifice, the home-cage locomotor activity was significantly diminished by the LPS-paraquat treatment. However, this decrement was most apparent in the mice that also received DSS earlier. *p < 0.05 compared to non-treated control mice. ***p < 0.001 compared to other water treatment groups

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