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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson’s disease

Fig. 6

Microglial activation was assessed using a validated semi-quantitative rating scale for morphology on ×20 images of SNc sections with IBA-1 (red) and TH (green) immunofluorescence. The DSS treatment alone significantly increased ratings of activation scoring (p < 0.05), as did the LPS and paraquat combination treatment (p < 0.001). But the VSL#3 treatment was without significant effect on microglial morphological ratings. *p < 0.05 compared to saline treated animals ***p < 0.001 compared to either: a control water-treated mice that received LPS + PQ infusion or b saline-infused mice that received DSS treatment

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