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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Chronic exposure to IL-6 induces a desensitized phenotype of the microglia

Fig. 5

Collateral sprouting. a Graph showing the time course of the selenium-silver staining for zinc (arrows) expressed as proportion of occupied area. Note that GFAP-IL6Tg animals showed a reduction of Zinc+ staining at 21dpl. b Representative images from WT and GFAP-IL6Tg mice, at 21 dpl, showing staining in the ML of the DG (GL indicates granular layer). Scale bar = 20 μm. At least three WT and five GFAP-IL6Tg animals (NL animals and at 14 and 21dpl) were analyzed. A total of 24 photographs from 8 different hippocampal sections per animal were quantified. Data are represented as mean ± SD. The significances are represented as: #p ≤ 0.05 vs. NL of respective group and $p ≤ 0.01 vs. NL of respective group. Significant differences between genotypes are represented as: *p ≤ 0.05

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