Skip to main content
Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein

Fig. 3

MiR-142 silence rescued the apoptosis of hippocampal neurons in PTSD rats. a, b The ratio of apoptosis in the control, PTSD, Sh-miR-NC, and Sh-miR groups after transfection with miR-142 inhibitor in rat hippocampus. c Western blot was used to detect the relative expression of Bax, caspase-3, and Bcl-2 in the hippocampus of rats in each group. Sample western blots for each protein are presented with β-actin as a loading control. The relative band intensity of d Bax, e caspase-3, and f Bcl-2 protein in each group. n = 6 rats per genotype. Bar graphs represent the mean ± SEM of independent experimental triplicates. One-way ANOVA followed by Bonferroni’s post hoc test; *P < 0.05, **P < 0.01

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094