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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: miR-142 downregulation alleviates rat PTSD-like behaviors, reduces the level of inflammatory cytokine expression and apoptosis in hippocampus, and upregulates the expression of fragile X mental retardation protein

Fig. 4

miR-142 could regulate the expression of Iba 1, p-p65 in rat hippocampus. a Representative image indicating Iba 1 (green) and p-p65 NF-κB (red) immunopositive cells in rat hippocampus of the control, PTSD, sh-miR-NC, and sh-miR groups. b The expression of Iba 1 and p-p65 NF-κB by western blot analysis in the hippocampi of rats in each group. Sample western blots for Iba 1 were presented with β-actin as a loading control, NF-κB p65 was used for a loading control to p-p65. The relative level of c Iba 1, and d p-p65 expression in each group. n = 6 rats per genotype. Bar graphs represent the mean ± SEM of independent experimental triplicates. One-way ANOVA followed by Bonferroni’s post hoc test; *P < 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094