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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Suppression of TLR4-MyD88 signaling pathway attenuated chronic mechanical pain in a rat model of endometriosis

Fig. 4

Endometriosis upregulated TLR4 in nociceptors. ah Double immunostaining showed co-expression of TLR4 with nociceptive marker, CGRP, IB4, and TRPV1 in rat DRG from sham and EM 14d groups. Scale bar 50 μm. i Parentages of TLR4+ cells in neurons with nociceptive markers (IB4, CGRP, and TRPV1) were increased in the EM 14d group compared with that in sham group. n > 100 neurons from 3 rats in each group, *p < 0.05, EM 14d vs sham, chi-square test

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