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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated neurological deficits

Fig. 6

Deficits in social behavior are induced by intestinal inflammation in Sham-injured and TBI mice. Neither TBI nor intestinal inflammation significantly altered sociability in mice a. Intestinal inflammation following craniotomy and TBI resulted in an impairment in social recognition and memory with both Sham+DSS and TBI + DSS mice spending significantly less time with the novel stimulus mouse over the familiar stimulus mouse compared to Sham and TBI mice, respectively b. Data expressed as mean ± s.e.m (n = 12–21/group). ^ p < 0.05 vs Naïve+DSS, ^^ p < 0.01 vs Naïve+DSS, + p < 0.05 vs Sham or TBI

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Journal of Neuroinflammation

ISSN: 1742-2094