Fig. 3

Effects of exogenous CypA and CypA small interfering RNA treatment on blood–brain barrier after subarachnoid hemorrhage. a Representative Western blot bands of the inhibition effect of CypA siRNA after SAH. b Quantitative analysis of the western blot bands in (a). c Modified Garcia test and d beam balance test results of each group at 24 h after SAH. e Modified Garcia test and f beam balance test results of each group at 24 h after SAH. g Brain water content assessment at 24 h after SAH. h Evans blue extravasation evaluation at 24 h after SAH. i Representative immunohistochemistry staining slices Collagen IV (Green) and Lectin (White) at 24 h after SAH. Arrow indicates the breakdown of continuous endothelia cell layer. n = 6. @: vs. sham P < 0.05, #: vs. SAH + vehicle P < 0.05, and $: vs. SAH + Scr siRNA P < 0.05