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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Cyclophilin a signaling induces pericyte-associated blood-brain barrier disruption after subarachnoid hemorrhage

Fig. 9

Changes of P-p65, MMP9, Collagen IV, and tight junction proteins expression after treatment at 24 h post subarachnoid hemorrhage. a Representative Western blot bands of MMP9 P-p65 and total p65 from ipsilateral hemisphere after SAH. Quantitative analyses of b MMP9, c P-p65, and total p65 d expressions from ipsilateral hemisphere after SAH. e Representative zymography bands and f quantitative analysis of MMP9 activities from ipsilateral hemisphere after SAH. g Representative bands and quantitative analysis of h ZO-1, i Collagen IV, j Occludin, and k Claudin 5 expressions in ipsilateral hemisphere of brain specimen at 24 h after SAH. Relative densities of each protein have been normalized against the sham group. n = 6 @: vs. sham P < 0.05, #: vs. SAH + Vehicle P < 0.05, and $: vs. SAH + CypA + Scr siRNA P < 0.05

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