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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Pre-treatment with the viral Toll-like receptor 3 agonist poly(I:C) modulates innate immunity and protects neutropenic mice infected intracerebrally with Escherichia coli

Fig. 7

IFN-γ and CCL5 levels remained consistently high in surviving neutropenic animals. Poly(I:C)-pre-treated animals surviving the infection showed significantly higher levels of IFN-γ in the a cerebellum and b spleen, and of c CCL5 in the spleen, compared to controls (P ≤ 0.005). Each symbol represents an individual mouse. Horizontal bars indicate median values. Statistical analysis was performed by the Mann-Whitney U test

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