Fig. 2

Serum metabolic parameters in wt and EMD mice under NCD and HFD for 14 weeks. (a–f) a Triglycerides (TG), b high-density lipoprotein (HDL), c cholesterol, d non-esterified fatty acid (NEFA), e leptin, and f insulin tests in wt and EMD mice fed with NCD or HFD for 14 weeks. All data are presented as the mean ± SEM. Statistical significance was based on one-way ANOVA followed by Games-Howell’s (a, c, d, and f) or Tukey’s (b and e) post hoc test. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001