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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge

Fig. 5

Glial activation markers in wt and EMD mice under NCD and HFD for 14 weeks. (a–c) a Protein levels of GFAP, and b Iba1 were significantly higher in HFD-fed wt mice compared to NCD fed animals. Upon NCD, GFAP expression was also significantly increased in EMD mice compared to wt mice. a, b Scatter plots with bars represent protein levels quantification in each animal group. c Representative western blots are shown. All data are presented as the mean ± SEM. Statistical significance was based on one-way ANOVA test followed by Games-Howell’s post hoc test (b and c). *P < 0.05

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