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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Amyloid beta and diabetic pathology cooperatively stimulate cytokine expression in an Alzheimer’s mouse model

Fig. 5

Plasma glucose and insulin levels correlate with brain cytokine expression in db/db and mixed models. a Profiles of cytokines correlated with glucose levels in db/db or APP/PS1xdb/db mice (mean ± SD in an iterative subsampling of 80% of samples). b Glucose levels significantly correlate with brain composite cytokine score on LV1. c Profiles of cytokines correlated with insulin levels in db/db or APP/PS1xdb/db mice ordered with respect to a (mean ± SD in an iterative subsampling of 80% of samples). d Plasma insulin concentration significantly correlated with brain composite cytokine score on LV1. Data were collected from 14 animals (8 M/6F, db/db 2 M/5F, APP/PS1xdb/db 6 M/1F)

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