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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Hypomethylation of nerve growth factor (NGF) promotes binding of C/EBPα and contributes to inflammatory hyperalgesia in rats

Fig. 6

Promoted binding of C/EBPα to the NGF gene promoter region in DRGs after CFA treatment. a Two predicted C/EBPα binding sites in the CpG islands of the NGF gene promoter. b, c Chromatin immunoprecipitation assays indicate a significant increase in binding activity of C/EBPα with the two sites of NGF gene promoter in CFA-induced inflammatory rats when compared with control rats (*P < 0.05, compared with the control group, n = 4 for each group)

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Journal of Neuroinflammation

ISSN: 1742-2094