From: Effects of inflammation on the kynurenine pathway in schizophrenia — a systematic review
Year | Author | Sample Size | Q1 | Q2 | Q3 | Q4 | Q5 | Q6 | Q7 | Q8 | Q9 | Q10 | Q11 | Q12 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Controls | Patients | ||||||||||||||
A. Immunoglobulins | |||||||||||||||
2017 | Kanchanatawan et al. | 40 | 84 clinically stable Sz outpatients | Yes | CD | NR | Yes | Yes | Yes | NR | Yes | NA | Yes | NR | Yes |
2018a | Kanchanatawan et al. | 40 | 80 Sz outpatients, 40 deficit, and 40 non-deficit patients | Yes | Yes | Yes | Yes | Yes | Yes | No | No | Yes | Yes | NA | Yes |
2018b | Kanchanatawan et al. | 40 | 80 Sz outpatients, 40 deficit, and 40 non-deficit patients | Yes | CD | Yes | Yes | Yes | Yes | NR | CD | NA | Yes | Yes | Yes |
2010 | Bechter et al. | 4100 | Inpatient Sz = 39, inpatient Af = 24 | Yes | Yes | No | Yes | Yes | Yes | No | No | Yes | Yes | NA | No |
B. Interleukins | |||||||||||||||
2017 | Szymona et al. | 45 | 51 Sz inpatients due to acute relapse at time of admission, after a 4-week treatment and remission | Yes | Yes | NR | Yes | Yes | Yes | NR | Yes | NA | Yes | Yes | Yes |
2009 | Barry et al. | 36 | 34 outpatients (Sz or SzA disorder | Yes | Yes | No | Yes | Yes | Yes | No | No | Yes | Yes | NA | Yes |
2009 | Kim et al. | 174 | 71 acute admitted medication-naïve psychotic patients or medication-free for at least 4 months assessed on admission and discharge after 6 weeks. | Yes | Yes | NR | Yes | Yes | Yes | NR | CD | NA | Yes | Yes | Yes |
2015 | Schwieler et al. | 37 | 23 Sz outpatients | Yes | Yes | No | Yes | Yes | Yes | No | No | Yes | Yes | NA | Yes |
2017 | Kegel et al. | Outpatient (MZ) | Outpatient (DZ) | Yes | Yes | No | Yes | Yes | Yes | No | No | Yes | Yes | NA | Yes |
12 (2 single twins) | 11 (one single twin) | ||||||||||||||
C. C-reactive protein | |||||||||||||||
2017 | Wurfel et al. | 92 | Inpatient MDD (N = 35), BD (N = 53), SzA (N = 40), acutely ill Sz (n = 21) | Yes | CD | NR | Yes | Yes | Yes | NR | CD | NA | Yes | Yes | Yes |