Fig. 5From: Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer’s diseaseRepresentative immunoblots and box plots showing FC levels of CHI3L1 (a), CHI3L2 (b), GFAP (c), CD44 (d), C1q (e), and NPTX2 (f) in NCI, MCI, mAD, and sAD. β-tubulin was used to normalize the immunoreactive signal obtained by densitometry. Statistical analysis revealed that CHI3L1, NPTX2, GFAP, and C1q protein levels were stable across clinical groups, whereas there was a significant decrease in CHI3L2 levels, and CD44 significantly increased in sAD compared to NCI (p = 0.001). Abbreviations: NCI, non-cognitive impairment; MCI, mild cognitive impairment; mAD, mild to moderate AD; sAD, severe ADBack to article page