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Table 1 Demographic data, metabolic profiles, and levels of pro-inflammatory cytokines between patients with bipolar disorder and unipolar depression

From: A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder

 

Bipolar disorder (n = 72)

Unipolar depression (n = 64)

P value

Demographic data

 Sex (M/F, n)

27/45

19/45

0.336

 Age (SD)

39.5 (12.3)

39.0 (15.3)

0.837

Metabolic profiles

 BMI (SD)

26.6 (5.2)

23.7 (4.03)

0.002*

 Glucose (SD)

89.8 (16.4)

89.1 (9.2)

0.758

 Triglyceride (SD)

119.5 (93.5)

107.4 (69.9)

0.400

 High density lipoprotein (HDL)

56.4 (16.9)

56.8 (13.4)

0.876

 Leptin (SD)

11,431.2 (10,944.5)

9013.4 (7372.7)

0.159

 Insulin (SD)

9.65 (14.78)

8.12 (14.04)

0.551

 Adiponectin (SD)

6158.4 (4670.2)

7505.1 (5664.9)

0.141

 Metabolic syndrome (%)

23.6%

22.6%

0.527

Inflammation index (pg/ml)

 sIL-6R (SD)

36,917.86 (11,001.38)

29,420.91 (8282.58)

< 0.001**

 sIL-2R (SD)

747.39 (323.22)

671.83 (246.70)

0.135

 CRP (SD)

1751.60 (1929.26)

1823.09 (2289.56)

0.840

 sTNFR1 (SD)

1216.55 (468.646)

748.46 (161.44)

< 0.001**

  1. BMI body mass index, SD standard deviation, MARDS Montgomery-Åsberg Depression Rating Scale, YAMRS The Young Mania Rating Scale; Global Assessment of Function Scale, sIL-2R soluble IL-2 receptor, sIL-6R soluble IL-6 receptor, CRP C-reactive protein, sTNFR1 soluble tumor necrosis factor-α receptor-1
  2. *P < 0.05, **P < 0.001