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Table 3 Comparison of cytokines in patients with bipolar disorder taking a different type of treatment

From: A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder

 

Li or VPA only (n = 11)

AA only (n = 18)

Li or VPA plus AA (n = 36)

Lamotrigine or carbamazepine (n = 7)

Significance

C-reactive protein (CRP) (pg/ml)

1725.3 ± 1053.7

1888.2 ± 2337.9

1701.7 ± 1449.0

1088.2 ± 1085.4

n.s.

Soluble interleukin-2 receptor (sIL-2R) (pg/ml)

692.3 ± 266.6

797.9 ± 337.5

760.2 ± 352.2

630.5 ± 250.1

n.s.

Soluble interleukin-6 receptor (sIL-6R) (pg/ml)

37,253.7 ± 6243.3

36,311.6 ± 10,217.6

38,994.4 ± 12,634.2

29,989.6 ± 8728.0

n.s.

Soluble tumor necrosis factor receptor type 1 (sTNF-R1) (pg/ml)

1203.3 ± 311.3

1050.6 ± 319.1

1319.2 ± 577.5

1158.1 ± 200.1

n.s.

  1. AA atypical antipsychotic, VPA valproic acid, n.s. not significant