A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder

Table 5 Correlation between gray matter volume reduction and levels of pro-inflammatory cytokines

Region	R. cerebellar lobule VIII	R. putamen	L. putamen	R. superior frontal gyrus	L. lingual gyrus	L. precentral gyrus	R. fusiform gyrus	L. calcarine	R. precuneus	L. inferior temporal gyrus	L. hippocampus	L. superior frontal gyrus
sTNFR1	− 0.324**	− 0.352**	− 0.360**	− 0.217*	− 0.196*	− 0.289**	− 0.335**	− 0.289**	− 0.195*	− 0.423**	−0.168	− 0.138
sIL-6R	− 0.173**	− 0.321**	− 0.355**	− 0.254**	− 0.181*	− 0.284**	− 0.188*	− 0.212*	− 0.176*	− 0.232**	− 0.099	− 0.194**
sIL-2R	− 0.048	− 0.109	− 0.103	− 0.028	− 0.013	− 0.098	− 0.104	− 0.120	− 0.047	− 0.121	0.007	0.003
CRP	0.007	− 0.054	− 0.033	− 0.058	− 0.010	− 0.006	0.019	− 0.038	0.117	− 0.085	− 0.110	0.007

R right, L left, sIL-2R soluble IL-2 receptor, sIL-6R soluble IL-6 receptor, CRP C-reactive protein, sTNFR1 soluble tumor necrosis factor-α receptor-1
Italicized data indicate the statistical significance
**p < 0.01, *p < 0.05

ISSN: 1742-2094