Fig. 4

miR-29b-3p in BMSC-derived exosomes ameliorates OGD-induced cell injury. a,b Apoptosis of cortical neurons after treated with BMSC-derived exosomes detected by TUNEL staining (scale bar = 50 μm). c, d The expression of neuronal apoptosis- and BMECs angiogenesis-related proteins analyzed by western blot analysis. e Representative images and quantification of tube formation ability of BMECs after treated with BMSC-derived exosomes (scale bar = 100 μm). *p < 0.05 vs. the NC mimic group, #p < 0.05 vs. the NC inhibitor group. The measurement data are expressed as mean ± standard deviation. The comparison between the two groups was carried out by the independent sample t test. The experiment was repeated in triplicate