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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway

Fig. 6

miR-29b-3p activates the Akt signaling pathway. Akt phosphorylation was detected in neurons infected with lentivirus harboring miR-29b-3p mimic or miR-29b-3p inhibitor (a, b), or PTEN shRNA (c, d). Akt phosphorylation was detected in BMECs infected with lentivirus harboring miR-29b-3p mimic or miR-29b-3p inhibitor (e, f), or PTEN shRNA (g, h). *p < 0.05 vs. the NC mimic group or vector group. The measurement data are expressed as mean ± standard deviation. The comparison between the two groups was carried out by the independent sample t test. The experiment was repeated three times

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