Skip to main content
Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis

Fig. 4

CXCR2+neutrophils are not required for microglial activation. a Representative images of Iba1 immunohistochemistry staining in lumbar spinal cord ventral horns of naïve control, control EAE, and Cxcr2 cKO EAE mice. Quantitative analysis of Iba1+ cell (b) soma area as shown in a. A total of 2338 Iba1+ cells were included in our analyses of soma size (cont naive, 222 Iba1 cells; control EAE, 1236 Iba1+ cells; Cxcr2 cKO EAE, 880 Iba1+ cells). Control naïve, n = 3; control EAE, n = 3; Cxcr2 cKO EAE, n = 3. *p < 0.05, two-tailed unpaired Student’s t test

Back to article page