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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Activated STAT3 signaling pathway by ligature-induced periodontitis could contribute to neuroinflammation and cognitive impairment in rats

Fig. 1

Timeline and intraoral photographs of periodontal ligature. a Timeline of the experiment. Periodontal ligature was placed for 8 weeks in the CP group and CP + CTS group, during which the CP + CTS group accepted CTS intraperitoneal injection every 3 days. After the last treatment, cognitive function was assessed by the OFT and MWM test. The underlying mechanism was further detected by RT-PCR, ELISA, WB, and IHC. b Representative intraoral photographs of 4 groups. Note the increased soft tissue edema around the ligature-treated molars compared to natural molar, and the edema was relived in the CP + CTS group

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