Fig. 5
From: Efficacy and tolerability of folate-aminopterin therapy in a rat focal model of multiple sclerosis
Body weights, digital autoradiography, histology, and immunofluorescence of healthy rats. The body weights of fDTH-EAE rats during acute (a) and chronic (b) phases of the disease and of healthy Lewis rats (c) with EC2319 or saline treatment. d Ex vivo 68Ga-FOL autoradiography, H&E histology, FR-β, CD68, iNOS, and MRC-1 immunofluorescence staining. Scale bars, 50 μm (high power) and 2 mm (low power)