Experimental groups | PaCO2 (mmHg) | PaO2 (mmHg) | SBEc mmol/L |
---|---|---|---|
Sham + vehicle + mAIH | |||
 Baseline | 44.0 ± 1.5 | 315 ± 11 | 1.13 ± 0.2 |
 Hypoxia | 43.6 ± 1.4 | 40 ± 1.0* | 1.35 ± 0.4 |
 30 min | 43.9 ± 1.7 | 256 ± 16* | 1.20 ± 0.4 |
 60 min | 44.2 ± 1.3 | 279 ± 2* | 1.75 ± 0.5 |
 90 min | 44.5 ± 1.5 | 265 ± 9* | 1.55 ± 0.5 |
LPS + vehicle + mAIH | |||
 Baseline | 42.4 ± 1.2 | 318 ± 10 | 0.3 ± 0.6 |
 Hypoxia | 42.3 ± 1.0 | 42 ± 1.3* | 0.8 ± 0.5 |
 30 min | 42.4 ± 1.1 | 270 ± 18* | 2.1 ± 0.7 |
 60 min | 42.2 ± 1.3 | 276 ± 11* | 1.6 ± 0.9 |
 90 min | 42.3 ± 1.2 | 283 ± 11* | 0.9 ± 0.9 |
Sham + okadaic acid + mAIH | |||
 Baseline | 43.8 ± 1.5 | 313 ± 10 | 1.3 ± 0.6 |
 Hypoxia | 44.0 ± 1.3 | 40 ± 2.4* | 0.1 ± 0.5 |
 30 min | 43.9 ± 0.8 | 249 ± 16* | 1.6 ± 0.67 |
 60 min | 43.9 ± 1.4 | 251 ± 22* | 0.6 ± 0.4 |
 90 min | 43.8 ± 0.9 | 240 ± 26* | − 0.4 ± 0.7 |
LPS + okadaic acid + mAIH | |||
 Baseline | 40.5 ± 1.0 | 317 ± 7.8 | 0.7 ± 0.6 |
 Hypoxia | 41.2 ± 1.1 | 40 ± 1.3* | 2.0 ± 0.3 |
 30 min | 40.6 ± 1.0 | 268 ± 14* | 2.4 ± 0.3 |
 60 min | 40.6 ± 0.7 | 268 ± 11* | 2.1 ± 0.3 |
 90 min | 41.2 ± 0.8 | 261 ± 12* | 1.6 ± 0.5 |