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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Oligodeoxynucleotides containing unmethylated cytosine-guanine motifs are effective immunostimulants against pneumococcal meningitis in the immunocompetent and neutropenic host

Fig. 6

Concentrations of interleukin (IL)-12/IL-23p40 and macrophage inflammatory protein (MIP)-1α in cerebellum and spleen of CpG ODN-stimulated and control neutropenic wild-type mice 24 h after infection. (a, b) Cerebellum. (c, d) Spleen. IL-12/IL-23p40 concentrations were higher both in the cerebellum and spleen, whereas MIP-1α levels were only higher in the spleens of CpG ODN-treated mice (a): one sample from one mouse of the buffer group below the level of detection; (b): one sample from one mouse pre-treated with CpG below the level of detection; (d): one sample from one mouse of the buffer group below the level of detection

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Journal of Neuroinflammation

ISSN: 1742-2094