Fig. 5
Treatment of WT mice with CryABR120G mice-derived exosomes worsened I/R-induced brain injury. a Diagrammatic illustration of the experimental design of treatment of WT mice with exosomes. b TTC staining of WT mouse brains treated with exosomes isolated from Ntg mice or CryABR120G mice. c Quantitative analysis of (b). d Survival rate of mice following MCAO and exosome treatment. e Neurological deficits following MCAO and exosome treatment. Data are shown as mean ± SD; n = 10 for Ntg-Exo treatment and n = 9 for CryAB-Exo treatment in (c–e). **p < 0.01, $p < 0.001